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Excess HB-EGF, which promotes VEGF signaling, leads to hydrocephalus

Heparin binding epidermal growth factor-like growth factor (HB-EGF) is an angiogenic factor mediating radial migration of the developing forebrain, while vascular endothelial growth factor (VEGF) is known to influence rostral migratory stream in rodents. Cell migratory defects have been identified i...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Shim, Joon W., Sandlund, Johanna, Hameed, Mustafa Q., Blazer-Yost, Bonnie, Zhou, Feng C., Klagsbrun, Michael, Madsen, Joseph R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4886677/
https://ncbi.nlm.nih.gov/pubmed/27243144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26794
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