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Excess HB-EGF, which promotes VEGF signaling, leads to hydrocephalus

Heparin binding epidermal growth factor-like growth factor (HB-EGF) is an angiogenic factor mediating radial migration of the developing forebrain, while vascular endothelial growth factor (VEGF) is known to influence rostral migratory stream in rodents. Cell migratory defects have been identified i...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Shim, Joon W., Sandlund, Johanna, Hameed, Mustafa Q., Blazer-Yost, Bonnie, Zhou, Feng C., Klagsbrun, Michael, Madsen, Joseph R.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4886677/
https://ncbi.nlm.nih.gov/pubmed/27243144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26794
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