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A highly soluble, non-phototoxic, non-fluorescent blebbistatin derivative

Blebbistatin is a commonly used molecular tool for the specific inhibition of various myosin II isoforms both in vitro and in vivo. Despite its popularity, the use of blebbistatin is hindered by its poor water-solubility (below 10 micromolar in aqueous buffer) and blue-light sensitivity, resulting i...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Várkuti, Boglárka H., Képiró, Miklós, Horváth, István Ádám, Végner, László, Ráti, Szilvia, Zsigmond, Áron, Hegyi, György, Lenkei, Zsolt, Varga, Máté, Málnási-Csizmadia, András
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4886532/
https://ncbi.nlm.nih.gov/pubmed/27241904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26141
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