A highly soluble, non-phototoxic, non-fluorescent blebbistatin derivative

Blebbistatin is a commonly used molecular tool for the specific inhibition of various myosin II isoforms both in vitro and in vivo. Despite its popularity, the use of blebbistatin is hindered by its poor water-solubility (below 10 micromolar in aqueous buffer) and blue-light sensitivity, resulting i...

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Udgivet i:Sci Rep
Main Authors: Várkuti, Boglárka H., Képiró, Miklós, Horváth, István Ádám, Végner, László, Ráti, Szilvia, Zsigmond, Áron, Hegyi, György, Lenkei, Zsolt, Varga, Máté, Málnási-Csizmadia, András
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4886532/
https://ncbi.nlm.nih.gov/pubmed/27241904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26141
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