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Structural Model of Weak Binding Actomyosin in the Prepowerstroke State

We present the first in silico model of the weak binding actomyosin in the initial powerstroke state, representing the actin binding-induced major structural changes in myosin. First, we docked an actin trimer to prepowerstroke myosin then relaxed the complex by a 100-ns long unrestrained molecular...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Várkuti, Boglárka H., Yang, Zhenhui, Malnasi-Csizmadia, Andras
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340411/
https://ncbi.nlm.nih.gov/pubmed/25416786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.606665
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