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Structural Model of Weak Binding Actomyosin in the Prepowerstroke State

We present the first in silico model of the weak binding actomyosin in the initial powerstroke state, representing the actin binding-induced major structural changes in myosin. First, we docked an actin trimer to prepowerstroke myosin then relaxed the complex by a 100-ns long unrestrained molecular...

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Pubblicato in:J Biol Chem
Autori principali: Várkuti, Boglárka H., Yang, Zhenhui, Malnasi-Csizmadia, Andras
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340411/
https://ncbi.nlm.nih.gov/pubmed/25416786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.606665
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