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Structural Model of Weak Binding Actomyosin in the Prepowerstroke State

We present the first in silico model of the weak binding actomyosin in the initial powerstroke state, representing the actin binding-induced major structural changes in myosin. First, we docked an actin trimer to prepowerstroke myosin then relaxed the complex by a 100-ns long unrestrained molecular...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Autores principales: Várkuti, Boglárka H., Yang, Zhenhui, Malnasi-Csizmadia, Andras
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340411/
https://ncbi.nlm.nih.gov/pubmed/25416786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.606665
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