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Structural Model of Weak Binding Actomyosin in the Prepowerstroke State

We present the first in silico model of the weak binding actomyosin in the initial powerstroke state, representing the actin binding-induced major structural changes in myosin. First, we docked an actin trimer to prepowerstroke myosin then relaxed the complex by a 100-ns long unrestrained molecular...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Várkuti, Boglárka H., Yang, Zhenhui, Malnasi-Csizmadia, Andras
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340411/
https://ncbi.nlm.nih.gov/pubmed/25416786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.606665
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