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Effect of allosteric inhibition of non-muscle myosin 2 on its intracellular diffusion

Subcellular dynamics of non-muscle myosin 2 (NM2) is crucial for a broad-array of cellular functions. To unveil mechanisms of NM2 pharmacological control, we determined how the dynamics of NM2 diffusion is affected by NM2′s allosteric inhibitors, i.e. blebbistatin derivatives, as compared to Y-27632...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Horváth, Ádám I., Gyimesi, Máté, Várkuti, Boglárka H., Képiró, Miklós, Szegvári, Gábor, Lőrincz, István, Hegyi, György, Kovács, Mihály, Málnási-Csizmadia, András
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7415145/
https://ncbi.nlm.nih.gov/pubmed/32769996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-69853-8
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