The IL-4/STAT6 signaling axis establishes a conserved microRNA signature in human and mouse macrophages regulating cell survival via miR-342-3p

BACKGROUND: IL-4-driven alternative macrophage activation and proliferation are characteristic features of both antihelminthic immune responses and wound healing in contrast to classical macrophage activation, which primarily occurs during inflammatory responses. The signaling pathways defining the...

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Veröffentlicht in:Genome Med
Hauptverfasser: Czimmerer, Zsolt, Varga, Tamas, Kiss, Mate, Vázquez, Cesaré Ovando, Doan-Xuan, Quang Minh, Rückerl, Dominik, Tattikota, Sudhir Gopal, Yan, Xin, Nagy, Zsuzsanna S., Daniel, Bence, Poliska, Szilard, Horvath, Attila, Nagy, Gergely, Varallyay, Eva, Poy, Matthew N., Allen, Judith E., Bacso, Zsolt, Abreu-Goodger, Cei, Nagy, Laszlo
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4886428/
https://ncbi.nlm.nih.gov/pubmed/27245778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-016-0315-y
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