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Distinct profiles of functional discrimination among G proteins determine the actions of G protein–coupled receptors
Members of the G protein coupled receptor (GPCR) family play key roles in many physiological functions and have been extensively exploited pharmacologically to treat diseases. Individual GPCRs exert diverse and distinct effects on cellular physiology and transduce signals by activating heterotrimeri...
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| Publicado no: | Sci Signal |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4886239/ https://ncbi.nlm.nih.gov/pubmed/26628681 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aab4068 |
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