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Distinct profiles of functional discrimination among G proteins determine the actions of G protein–coupled receptors

Members of the G protein coupled receptor (GPCR) family play key roles in many physiological functions and have been extensively exploited pharmacologically to treat diseases. Individual GPCRs exert diverse and distinct effects on cellular physiology and transduce signals by activating heterotrimeri...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Signal
Egile Nagusiak: Masuho, Ikuo, Ostrovskaya, Olga, Kramer, Grant M., Jones, Christopher D., Xie, Keqiang, Martemyanov, Kirill A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4886239/
https://ncbi.nlm.nih.gov/pubmed/26628681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aab4068
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