Distinct profiles of functional discrimination among G proteins determine the actions of G protein–coupled receptors

Members of the G protein coupled receptor (GPCR) family play key roles in many physiological functions and have been extensively exploited pharmacologically to treat diseases. Individual GPCRs exert diverse and distinct effects on cellular physiology and transduce signals by activating heterotrimeri...

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Detaylı Bibliyografya
Yayımlandı:Sci Signal
Asıl Yazarlar: Masuho, Ikuo, Ostrovskaya, Olga, Kramer, Grant M., Jones, Christopher D., Xie, Keqiang, Martemyanov, Kirill A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4886239/
https://ncbi.nlm.nih.gov/pubmed/26628681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aab4068
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