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High Throughput Physiological Screening of iPSC-Derived Cardiomyocytes for Drug Development

Cardiac drug discovery is hampered by the reliance on non-human animal and cellular models with inadequate throughput and physiological fidelity to accurately identify new targets and test novel therapeutic strategies. Similarly, adverse drug effects on the heart are challenging to model, contributi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biochim Biophys Acta
Hauptverfasser: del Álamo, Juan Carlos, Lemons, Derek, Serrano, Ricardo, Savchenko, Alex, Cerignoli, Fabio, Bodmer, Rolf, Mercola, Mark
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4885786/
https://ncbi.nlm.nih.gov/pubmed/26952934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2016.03.003
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