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High Throughput Physiological Screening of iPSC-Derived Cardiomyocytes for Drug Development

Cardiac drug discovery is hampered by the reliance on non-human animal and cellular models with inadequate throughput and physiological fidelity to accurately identify new targets and test novel therapeutic strategies. Similarly, adverse drug effects on the heart are challenging to model, contributi...

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Dades bibliogràfiques
Publicat a:Biochim Biophys Acta
Autors principals: del Álamo, Juan Carlos, Lemons, Derek, Serrano, Ricardo, Savchenko, Alex, Cerignoli, Fabio, Bodmer, Rolf, Mercola, Mark
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4885786/
https://ncbi.nlm.nih.gov/pubmed/26952934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2016.03.003
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