An Automated Platform for Assessment of Congenital and Drug-Induced Arrhythmia with hiPSC-Derived Cardiomyocytes

The ability to produce unlimited numbers of human induced pluripotent stem cell derived cardiomyocytes (hiPSC-CMs) harboring disease and patient-specific gene variants creates a new paradigm for modeling congenital heart diseases (CHDs) and predicting proarrhythmic liabilities of drug candidates. Ho...

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Detalles Bibliográficos
Publicado en:Front Physiol
Main Authors: McKeithan, Wesley L., Savchenko, Alex, Yu, Michael S., Cerignoli, Fabio, Bruyneel, Arne A. N., Price, Jeffery H., Colas, Alexandre R., Miller, Evan W., Cashman, John R., Mercola, Mark
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2017
Assuntos:
Physiology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5641590/
https://ncbi.nlm.nih.gov/pubmed/29075196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2017.00766
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