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Experimental Evaluation of Proposed Small-Molecule Inhibitors of Water Channel Aquaporin-1
The aquaporin-1 (AQP1) water channel is a potentially important drug target, as AQP1 inhibition is predicted to have therapeutic action in edema, tumor growth, glaucoma, and other conditions. Here, we measured the AQP1 inhibition efficacy of 12 putative small-molecule AQP1 inhibitors reported in six...
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| Udgivet i: | Mol Pharmacol |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The American Society for Pharmacology and Experimental Therapeutics
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4885500/ https://ncbi.nlm.nih.gov/pubmed/26993802 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.116.103929 |
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