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The aquaporin-4 water channel as a potential drug target in neurological disorders

INTRODUCTION: Aquaporin-4 (AQP4) is a water transporting protein expressed at the plasma membrane of astrocytes throughout the central nervous system (CNS). Analysis of AQP4 knockout mice has suggested its broad involvement in brain water balance, neuroexcitation, glial scarring, neuroinflammation,...

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Bibliografiske detaljer
Udgivet i:Expert Opin Ther Targets
Main Authors: Verkman, Alan S., Smith, Alex J., Phuan, Puay-wah, Tradtrantip, Lukmanee, Anderson, Marc O.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6481624/
https://ncbi.nlm.nih.gov/pubmed/29072508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14728222.2017.1398236
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