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The aquaporin-4 water channel as a potential drug target in neurological disorders
INTRODUCTION: Aquaporin-4 (AQP4) is a water transporting protein expressed at the plasma membrane of astrocytes throughout the central nervous system (CNS). Analysis of AQP4 knockout mice has suggested its broad involvement in brain water balance, neuroexcitation, glial scarring, neuroinflammation,...
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| Publicado en: | Expert Opin Ther Targets |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6481624/ https://ncbi.nlm.nih.gov/pubmed/29072508 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14728222.2017.1398236 |
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