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The aquaporin-4 water channel as a potential drug target in neurological disorders

INTRODUCTION: Aquaporin-4 (AQP4) is a water transporting protein expressed at the plasma membrane of astrocytes throughout the central nervous system (CNS). Analysis of AQP4 knockout mice has suggested its broad involvement in brain water balance, neuroexcitation, glial scarring, neuroinflammation,...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Expert Opin Ther Targets
Prif Awduron: Verkman, Alan S., Smith, Alex J., Phuan, Puay-wah, Tradtrantip, Lukmanee, Anderson, Marc O.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6481624/
https://ncbi.nlm.nih.gov/pubmed/29072508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14728222.2017.1398236
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