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Classical cleidocranial dysplasia in an adult, due to a novel frameshift pathogenic variant in RUNX2

Cleidocranial dysplasia (CCD) is a rare genetic disorder of bone, characterised by hypoplastic/aplastic clavicles, delayed closure of fontanelles and sutures of the cranium and dental abnormalities. We describe a novel frameshift pathogenic variation—c.470dupT (p.M157Ifs*4, NM_001024630) in the runt...

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Bibliografiske detaljer
Udgivet i:BMJ Case Rep
Main Authors: Hebbar, Malavika, Girisha, Katta M, Shukla, Anju
Format: Artigo
Sprog:Inglês
Udgivet: BMJ Publishing Group 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4885364/
https://ncbi.nlm.nih.gov/pubmed/27177937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bcr-2016-215162
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