CD4 memory T cells develop and acquire functional competence by sequential cognate interactions and stepwise gene regulation

Memory CD4(+) T cells promote protective humoral immunity; however, how memory T cells acquire this activity remains unclear. This study demonstrates that CD4(+) T cells develop into antigen-specific memory T cells that can promote the terminal differentiation of memory B cells far more effectively...

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Vydáno v:Int Immunol
Hlavní autoři: Kaji, Tomohiro, Hijikata, Atsushi, Ishige, Akiko, Kitami, Toshimori, Watanabe, Takashi, Ohara, Osamu, Yanaka, Noriyuki, Okada, Mariko, Shimoda, Michiko, Taniguchi, Masaru, Takemori, Toshitada
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4885215/
https://ncbi.nlm.nih.gov/pubmed/26714588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxv071
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