Long lasting MDM2/Translocator protein modulator: a new strategy for irreversible apoptosis of human glioblastoma cells

The development of multi-target drugs and irreversible modulators of deregulated signalling proteins is the major challenge for improving glioblastoma multiforme (GBM) treatment. Reversible single-target drugs are not sufficient to sustain a therapeutic effect over time and may favour the activation...

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Publicado en:Oncotarget
Autores principales: Daniele, Simona, Barresi, Elisabetta, Zappelli, Elisa, Marinelli, Luciana, Novellino, Ettore, Da Settimo, Federico, Taliani, Sabrina, Trincavelli, Maria L., Martini, Claudia
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4884960/
https://ncbi.nlm.nih.gov/pubmed/26761214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6872
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