Apoptosis Therapy in Cancer: The First Single-molecule Co-activating p53 and the Translocator Protein in Glioblastoma

In the complex scenario of cancer, treatment with compounds targeting multiple cell pathways has been emerging. In Glioblastoma Multiforme (GBM), p53 and Translocator Protein (TSPO), both acting as apoptosis inducers, represent two attractive intracellular targets. On this basis, novel indolylglyoxy...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Daniele, Simona, Taliani, Sabrina, Da Pozzo, Eleonora, Giacomelli, Chiara, Costa, Barbara, Trincavelli, Maria Letizia, Rossi, Leonardo, La Pietra, Valeria, Barresi, Elisabetta, Carotenuto, Alfonso, Limatola, Antonio, Lamberti, Anna, Marinelli, Luciana, Novellino, Ettore, Da Settimo, Federico, Martini, Claudia
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2014
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3996484/
https://ncbi.nlm.nih.gov/pubmed/24756113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep04749
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