HDAC3 mediates smoking-induced pancreatic cancer

Smoking is a major risk factor for developing pancreatic adenocarcinoma (PDAC); however, little is known about the mechanisms involved. Here we employed a genetic animal model of early stages of PDAC that overexpresses oncogenic Kras in the pancreas to investigate the mechanisms of smoking-induced p...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Edderkaoui, Mouad, Xu, Shiping, Chheda, Chintan, Morvaridi, Susan, Hu, Robert W., Grippo, Paul J., Mascariñas, Emman, Principe, Daniel R., Knudsen, Beatrice, Xue, Jing, Habtezion, Aida, Uyeminami, Dale, Pinkerton, Kent E., Pandol, Stephen J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4884951/
https://ncbi.nlm.nih.gov/pubmed/26745602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6820
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