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Akt Kinase Mediates the Pro-Survival Effect of Smoking Compounds in Pancreatic Ductal Cells

OBJECTIVES: Cigarette smoking is a major risk factor for pancreatic cancer (PaCa). However, the mechanisms of smoking-induced PaCa remain unknown. Here we investigated the effect of smoking compounds on cell death pathways in pancreatic ductal cells, precursors of PaCa. METHODS: Human pancreatic duc...

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Bibliografske podrobnosti
Main Authors: Park, Chang-Hwan, Lee, In-Seok, Grippo, Paul, Pandol, Stephen J., Gukovskaya, Anna S., Edderkaoui, Mouad
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4085048/
https://ncbi.nlm.nih.gov/pubmed/23271397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPA.0b013e3182762928
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