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RNF138 interacts with RAD51D and is required for DNA interstrand crosslink repair and maintaining chromosome integrity

The RAD51 family is integral for homologous recombination (HR) mediated DNA repair and maintaining chromosome integrity. RAD51D, the fourth member of the family, is a known ovarian cancer susceptibility gene and required for the repair of interstrand crosslink DNA damage and preserving chromosomal s...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:DNA Repair (Amst)
Hauptverfasser: Yard, Brian D., Reilly, Nicole M., Bedenbaugh, Michael K., Pittman, Douglas L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4884500/
https://ncbi.nlm.nih.gov/pubmed/27161866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2016.04.006
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