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Ubiquitylation of Rad51d Mediated by E3 Ligase Rnf138 Promotes the Homologous Recombination Repair Pathway

Ubiquitylation has an important role as a signal transducer that regulates protein function, subcellular localization, or stability during the DNA damage response. In this study, we show that Ring domain E3 ubiquitin ligases RNF138 is recruited to DNA damage site quickly. And the recruitment is medi...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Han, Deqiang, Liang, Junbo, Lu, Yalan, Xu, Longchang, Miao, Shiying, Lu, Lin-Yu, Song, Wei, Wang, Linfang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4873259/
https://ncbi.nlm.nih.gov/pubmed/27195665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0155476
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