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Mechanism of RAD51dependent DNA interstrand crosslink repair
DNA interstrand cross-links (ICLs) are toxic DNA lesions whose repair in S phase of eukaryotic cells is incompletely understood. In Xenopus egg extracts, ICL repair is initiated when two replication forks converge on the lesion. Dual incisions then create a DNA double-strand break (DSB) in one siste...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4068331/ https://ncbi.nlm.nih.gov/pubmed/21719678 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1204258 |
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