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Mechanism of RAD51dependent DNA interstrand crosslink repair

DNA interstrand cross-links (ICLs) are toxic DNA lesions whose repair in S phase of eukaryotic cells is incompletely understood. In Xenopus egg extracts, ICL repair is initiated when two replication forks converge on the lesion. Dual incisions then create a DNA double-strand break (DSB) in one siste...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Long, David T., Räschle, Markus, Joukov, Vladimir, Walter, Johannes C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068331/
https://ncbi.nlm.nih.gov/pubmed/21719678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1204258
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