TIMP3 Modulates GHR Abundance and GH Sensitivity

GH receptor (GHR) binds GH at the cell surface via its extracellular domain and initiates intracellular signal transduction, resulting in important anabolic and metabolic actions. GH signaling is subject to dynamic regulation, which in part is exerted by modulation of cell surface GHR levels. Consti...

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Detaylı Bibliyografya
Yayımlandı:Mol Endocrinol
Asıl Yazarlar: Zhang, Yue, Wang, Xiangdong, Loesch, Kimberly, May, Larry A., Davis, George E., Jiang, Jing, Frank, Stuart J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Endocrine Society 2016
Konular:
Original Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4884343/
https://ncbi.nlm.nih.gov/pubmed/27075707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2015-1302
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