Distinct patterns of somatic genome alterations in lung adenocarcinomas and squamous cell carcinomas

To compare lung adenocarcinoma (ADC) and lung squamous cell carcinoma (SqCC) and to identify new drivers of lung carcinogenesis, we examined exome sequences and copy number profiles of 660 lung ADC and 484 lung SqCC tumor/normal pairs. Recurrent alterations in lung SqCCs were more similar to other s...

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Publicado no:Nat Genet
Main Authors: Campbell, Joshua D., Alexandrov, Anton, Kim, Jaegil, Wala, Jeremiah, Berger, Alice H., Pedamallu, Chandra Sekhar, Shukla, Sachet A., Guo, Guangwu, Brooks, Angela N., Murray, Bradley A., Imielinski, Marcin, Hu, Xin, Ling, Shiyun, Akbani, Rehan, Rosenberg, Mara, Cibulskis, Carrie, Ramachandran, Aruna, Collisson, Eric A., Kwiatkowski, David J., Lawrence, Michael S., Weinstein, John N., Verhaak, Roel G. W., Wu, Catherine J., Hammerman, Peter S., Cherniack, Andrew D., Getz, Gad, Artyomov, Maxim N., Schreiber, Robert, Govindan, Ramaswamy, Meyerson, Matthew
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4884143/
https://ncbi.nlm.nih.gov/pubmed/27158780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3564
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