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An mDia1-INF2 formin activation cascade facilitated by IQGAP1 regulates stable microtubules in migrating cells
Multiple formins regulate microtubule (MT) arrays, but whether they function individually or in a common pathway is unknown. Lysophosphatidic acid (LPA) stimulates the formation of stabilized detyrosinated MTs (Glu MTs) in NIH3T3 fibroblasts through RhoA and the formin mDia1. Here we show that anoth...
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| izdano v: | Mol Biol Cell |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The American Society for Cell Biology
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4884070/ https://ncbi.nlm.nih.gov/pubmed/27030671 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-07-0489 |
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