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An mDia1-INF2 formin activation cascade facilitated by IQGAP1 regulates stable microtubules in migrating cells

Multiple formins regulate microtubule (MT) arrays, but whether they function individually or in a common pathway is unknown. Lysophosphatidic acid (LPA) stimulates the formation of stabilized detyrosinated MTs (Glu MTs) in NIH3T3 fibroblasts through RhoA and the formin mDia1. Here we show that anoth...

詳細記述

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書誌詳細
出版年:Mol Biol Cell
主要な著者: Bartolini, Francesca, Andres-Delgado, Laura, Qu, Xiaoyi, Nik, Sara, Ramalingam, Nagendran, Kremer, Lenor, Alonso, Miguel A., Gundersen, Gregg G.
フォーマット: Artigo
言語:Inglês
出版事項: The American Society for Cell Biology 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4884070/
https://ncbi.nlm.nih.gov/pubmed/27030671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-07-0489
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