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Kif4 Interacts with EB1 and Stabilizes Microtubules Downstream of Rho-mDia in Migrating Fibroblasts

Selectively stabilized microtubules (MTs) form in the lamella of fibroblasts and contribute to cell migration. A Rho-mDia-EB1 pathway regulates the formation of stable MTs, yet how selective stabilization of MTs is achieved is unknown. Kinesin activity has been implicated in selective MT stabilizati...

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Detalhes bibliográficos
Main Authors: Morris, Edward J., Nader, Guilherme P. F., Ramalingam, Nagendran, Bartolini, Francesca, Gundersen, Gregg G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3962350/
https://ncbi.nlm.nih.gov/pubmed/24658398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0091568
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