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Actin-capping protein promotes microtubule stability by antagonizing the actin activity of mDia1

In migrating fibroblasts, RhoA and its effector mDia1 regulate the selective stabilization of microtubules (MTs) polarized in the direction of migration. The conserved formin homology 2 domain of mDia1 is involved both in actin polymerization and MT stabilization, and the relationship between these...

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Bibliographic Details
Main Authors: Bartolini, Francesca, Ramalingam, Nagendran, Gundersen, Gregg G.
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469518/
https://ncbi.nlm.nih.gov/pubmed/22918941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-05-0338
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