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Actin-capping protein promotes microtubule stability by antagonizing the actin activity of mDia1

In migrating fibroblasts, RhoA and its effector mDia1 regulate the selective stabilization of microtubules (MTs) polarized in the direction of migration. The conserved formin homology 2 domain of mDia1 is involved both in actin polymerization and MT stabilization, and the relationship between these...

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Detalhes bibliográficos
Main Authors: Bartolini, Francesca, Ramalingam, Nagendran, Gundersen, Gregg G.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469518/
https://ncbi.nlm.nih.gov/pubmed/22918941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-05-0338
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