Aminothiazoles inhibit RANKL‐ and LPS‐mediated osteoclastogenesis and PGE (2) production in RAW 264.7 cells

Periodontitis is characterized by chronic inflammation and osteoclast‐mediated bone loss regulated by the receptor activator of nuclear factor‐κB (RANK), RANK ligand (RANKL) and osteoprotegerin (OPG). The aim of this study was to investigate the effect of aminothiazoles targeting prostaglandin E syn...

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Publicado en:J Cell Mol Med
Main Authors: Kats, Anna, Norgård, Maria, Wondimu, Zenebech, Koro, Catalin, Concha Quezada, Hernán, Andersson, Göran, Yucel‐Lindberg, Tülay
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2016
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Original Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4882984/
https://ncbi.nlm.nih.gov/pubmed/26987561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12814
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