Aminothiazoles inhibit RANKL‐ and LPS‐mediated osteoclastogenesis and PGE (2) production in RAW 264.7 cells

Periodontitis is characterized by chronic inflammation and osteoclast‐mediated bone loss regulated by the receptor activator of nuclear factor‐κB (RANK), RANK ligand (RANKL) and osteoprotegerin (OPG). The aim of this study was to investigate the effect of aminothiazoles targeting prostaglandin E syn...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Kats, Anna, Norgård, Maria, Wondimu, Zenebech, Koro, Catalin, Concha Quezada, Hernán, Andersson, Göran, Yucel‐Lindberg, Tülay
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4882984/
https://ncbi.nlm.nih.gov/pubmed/26987561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12814
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