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Aminothiazoles inhibit RANKL‐ and LPS‐mediated osteoclastogenesis and PGE (2) production in RAW 264.7 cells

Periodontitis is characterized by chronic inflammation and osteoclast‐mediated bone loss regulated by the receptor activator of nuclear factor‐κB (RANK), RANK ligand (RANKL) and osteoprotegerin (OPG). The aim of this study was to investigate the effect of aminothiazoles targeting prostaglandin E syn...

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Dettagli Bibliografici
Pubblicato in:J Cell Mol Med
Autori principali: Kats, Anna, Norgård, Maria, Wondimu, Zenebech, Koro, Catalin, Concha Quezada, Hernán, Andersson, Göran, Yucel‐Lindberg, Tülay
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4882984/
https://ncbi.nlm.nih.gov/pubmed/26987561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12814
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