MUC1-C drives MYC in multiple myeloma

Multiple myeloma (MM) cell lines and primary tumor cells are addicted to the MYC oncoprotein for survival. Little is known, however, about how MYC expression is upregulated in MM cells. The mucin 1 C-terminal subunit (MUC1-C) is an oncogenic transmembrane protein that is aberrantly expressed in MM c...

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Bibliografiske detaljer
Udgivet i:Blood
Main Authors: Tagde, Ashujit, Rajabi, Hasan, Bouillez, Audrey, Alam, Maroof, Gali, Reddy, Bailey, Shannon, Tai, Yu-Tzu, Hideshima, Teru, Anderson, Kenneth, Avigan, David, Kufe, Donald
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2016
Fag:
Lymphoid Neoplasia
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4882805/
https://ncbi.nlm.nih.gov/pubmed/26907633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-07-659151
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