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MUC1-C IS A TARGET IN LENALIDOMIDE RESISTANT MULTIPLE MYELOMA
Lenalidomide (LEN) acts directly on multiple myeloma (MM) cells by inducing cereblon-mediated degradation of interferon regulatory factor 4, Ikaros (IKZF)1 and IKZF3, transcription factors that are essential for MM cell survival. The mucin 1 (MUC1) C-terminal transmembrane subunit (MUC1-C) oncoprote...
Gorde:
| Argitaratua izan da: | Br J Haematol |
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| Egile Nagusiak: | , , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2017
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5591051/ https://ncbi.nlm.nih.gov/pubmed/28643330 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bjh.14801 |
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