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NAMPT knockdown attenuates atherosclerosis and promotes reverse cholesterol transport in ApoE KO mice with high-fat-induced insulin resistance

NAMPT has been suggested association with atherosclerosis and insulin resistance. However, the impact of NAMPT on atherosclerosis remained unknown. Therefore, the objective of this study was to use a NAMPT loss-of-function approach to investigate the effect of NAMPT on atherosclerosis in hypercholes...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Li, Shengbing, Wang, Cong, Li, Ke, Li, Ling, Tian, Mingyuan, Xie, Jing, Yang, Mengliu, Jia, Yanjun, He, Junying, Gao, Lin, Boden, Guenther, Liu, Hua, Yang, Gangyi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4882618/
https://ncbi.nlm.nih.gov/pubmed/27229177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26746
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