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NAMPT knockdown attenuates atherosclerosis and promotes reverse cholesterol transport in ApoE KO mice with high-fat-induced insulin resistance

NAMPT has been suggested association with atherosclerosis and insulin resistance. However, the impact of NAMPT on atherosclerosis remained unknown. Therefore, the objective of this study was to use a NAMPT loss-of-function approach to investigate the effect of NAMPT on atherosclerosis in hypercholes...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Li, Shengbing, Wang, Cong, Li, Ke, Li, Ling, Tian, Mingyuan, Xie, Jing, Yang, Mengliu, Jia, Yanjun, He, Junying, Gao, Lin, Boden, Guenther, Liu, Hua, Yang, Gangyi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4882618/
https://ncbi.nlm.nih.gov/pubmed/27229177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26746
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