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Nesfatin-1 Action in the Brain Increases Insulin Sensitivity Through Akt/AMPK/TORC2 Pathway in Diet-Induced Insulin Resistance

Nesfatin-1, derived from nucleobindin 2, was recently identified as an anorexigenic signal peptide. However, its neural role in glucose homeostasis and insulin sensitivity is unknown. To evaluate the metabolic impact and underlying mechanisms of central nesfatin-1 signaling, we infused nesfatin-1 in...

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Detalhes bibliográficos
Main Authors: Yang, Mengliu, Zhang, Zhihong, Wang, Chong, Li, Ke, Li, Shengbing, Boden, Guenther, Li, Ling, Yang, Gangyi
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3402309/
https://ncbi.nlm.nih.gov/pubmed/22688332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-1755
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