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ApoF knockdown increases cholesteryl ester transfer to LDL and impairs cholesterol clearance in fat-fed hamsters

Cholesteryl ester transfer protein (CETP) regulates intravascular lipoprotein metabolism. In vitro studies indicate that ApoF alters CETP function by inhibiting its activity with LDL. To explore in vivo the complexities driving ApoF’s effects on CETP, we developed a siRNA-based hamster model of ApoF...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Morton, Richard E., Liu, Yan, Izem, Lahoucine
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6824501/
https://ncbi.nlm.nih.gov/pubmed/31511396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.RA119000171
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