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Translation from the 5′ untranslated region shapes the integrated stress response
Translated regions distinct from annotated coding sequences have emerged as essential elements of the proteome. This includes upstream open reading frames (uORFs) present in mRNAs controlled by the integrated stress response (ISR) that show “privileged” translation despite inhibited eukaryotic initi...
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| Опубликовано в: : | Science |
|---|---|
| Главные авторы: | , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4882168/ https://ncbi.nlm.nih.gov/pubmed/26823435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aad3867 |
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