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Translation from the 5′ untranslated region shapes the integrated stress response

Translated regions distinct from annotated coding sequences have emerged as essential elements of the proteome. This includes upstream open reading frames (uORFs) present in mRNAs controlled by the integrated stress response (ISR) that show “privileged” translation despite inhibited eukaryotic initi...

詳細記述

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書誌詳細
出版年:Science
主要な著者: Starck, Shelley R., Tsai, Jordan C., Chen, Keling, Shodiya, Michael, Wang, Lei, Yahiro, Kinnosuke, Martins-Green, Manuela, Shastri, Nilabh, Walter, Peter
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4882168/
https://ncbi.nlm.nih.gov/pubmed/26823435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aad3867
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