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Nowhere to hide. Unconventional translation yields cryptic peptides for immune surveillance

Effective immune surveillance by CD8+ cytotoxic T cells of intracellular microbes and cancer depends upon the antigen presentation pathway. This pathway produces an optimal peptide repertoire for presentation by MHC class I molecules (pMHC I) on the cell surface. We have known for years that the pMH...

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Publicat a:Immunol Rev
Autors principals: Starck, Shelley R., Shastri, Nilabh
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4916849/
https://ncbi.nlm.nih.gov/pubmed/27319338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12434
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