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The Synthesis of Truncated Polypeptides for Immune Surveillance and Viral Evasion

BACKGROUND: Cytotoxic T cells detect intracellular pathogens by surveying peptide loaded MHC class I molecules (pMHC I) on the cell surface. Effective immune surveillance also requires infected cells to present pMHC I promptly before viral progeny can escape. Rapid pMHC I presentation apparently occ...

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Detalhes bibliográficos
Main Authors: Cardinaud, Sylvain, Starck, Shelley R., Chandra, Piyanka, Shastri, Nilabh
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2809100/
https://ncbi.nlm.nih.gov/pubmed/20098683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008692
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