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Up-regulation of the interferon-related genes in BRCA2 knockout epithelial cells

BRCA2 mutations are significantly associated with early onset breast cancer, and the tumour suppressing function of BRCA2 has been attributed to its involvement in homologous recombination [1]-mediated DNA repair. In order to identify additional functions of BRCA2, we generated BRCA2-knockout HCT116...

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Détails bibliographiques
Publié dans:J Pathol
Auteurs principaux: Xu, Hong, Xian, Jian, Vire, Emmanuelle, McKinney, Steven, Wong, Jason, Wei, Vivien, Tong, Rebecca, Kouzarides, Tony, Caldas, Carlos, Aparicio, Samuel
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4882165/
https://ncbi.nlm.nih.gov/pubmed/25043256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4404
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