BRCA immunohistochemistry for screening of BRCA mutation in epithelial ovarian cancer patients

To evaluate BRCA1/2 immunohistochemistry (IHC) as a screening test for germline BRCA1/2 in epithelial ovarian cancer (EOC), tumor tissue from 105 EOC patients who had germline BRCA mutations, including 9 BRCA1 mutations, 6 BRCA2 mutations and 90 no BRCA mutations, were studied. Paraffin-embedded tis...

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Detalhes bibliográficos
Publicado no:Gynecol Oncol Rep
Main Authors: Manchana, Tarinee, Tantbirojn, Patou, Pohthipornthawat, Natkrita
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Special Section on Global Gynecologic Oncology; Edited by Linus Chuang and Thomas Randall
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7276421/
https://ncbi.nlm.nih.gov/pubmed/32529018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gore.2020.100582
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