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Crystal Structure of the FERM-SH2 Module of Human Jak2
Jak-family tyrosine kinases mediate signaling from diverse cytokine receptors. Binding of Jaks to their cognate receptors is mediated by their N-terminal region, which contains FERM and SH2 domains. Here we describe the crystal structure of the FERM-SH2 region of Jak2 at 3.0Å resolution. The structu...
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| Udgivet i: | PLoS One |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4881981/ https://ncbi.nlm.nih.gov/pubmed/27227461 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0156218 |
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