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Connecting the Dots: From DNA Damage and Repair to Aging
Mammalian cells evolve a delicate system, the DNA damage response (DDR) pathway, to monitor genomic integrity and to prevent the damage from both endogenous end exogenous insults. Emerging evidence suggests that aberrant DDR and deficient DNA repair are strongly associated with cancer and aging. Our...
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| Udgivet i: | Int J Mol Sci |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MDPI
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4881511/ https://ncbi.nlm.nih.gov/pubmed/27164092 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17050685 |
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