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Connecting the Dots: From DNA Damage and Repair to Aging

Mammalian cells evolve a delicate system, the DNA damage response (DDR) pathway, to monitor genomic integrity and to prevent the damage from both endogenous end exogenous insults. Emerging evidence suggests that aberrant DDR and deficient DNA repair are strongly associated with cancer and aging. Our...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Pan, Mei-Ren, Li, Kaiyi, Lin, Shiaw-Yih, Hung, Wen-Chun
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4881511/
https://ncbi.nlm.nih.gov/pubmed/27164092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17050685
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