SARS Coronavirus Papain-Like Protease Inhibits the TLR7 Signaling Pathway through Removing Lys63-Linked Polyubiquitination of TRAF3 and TRAF6

Severe acute respiratory syndrome coronavirus (SARS-CoV) papain-like protease (PLPro) reportedly inhibits the production of type I interferons (IFNs) and pro-inflammatory cytokines in Toll-like receptor 3 (TLR3) and retinoic acid-inducible gene 1 (RIG-I) pathways. The study investigated the inhibito...

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Gepubliceerd in:Int J Mol Sci
Hoofdauteurs: Li, Shih-Wen, Wang, Ching-Ying, Jou, Yu-Jen, Huang, Su-Hua, Hsiao, Li-Hsin, Wan, Lei, Lin, Ying-Ju, Kung, Szu-Hao, Lin, Cheng-Wen
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4881504/
https://ncbi.nlm.nih.gov/pubmed/27164085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17050678
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